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In accordance with the current data protection regulations, ISGlobal informs you of the following: DOI: 10.3389/fnagi.2014.00051.Ĭosín-Tomás M., Luan Y., Leclerc D., Malysheva OV., Lauzon N., Bahous RH., Christensen KE., Caudill MA., Rozen R. Epigenetic alterations in hippocampus of SAMP8 senescent mice and modulation by voluntary physical exercise. Plasma miR-34a-5p and miR-545-3p as Early Biomarkers of Alzheimer's Disease: Potential and Limitations. Early Manifestations of Brain Aging in Mice Due to Low Dietary Folate and Mild MTHFR Deficiency. Differential DNA methylation in experienced meditators after an intensive day of mindfulness-based practice: Implications for immune-related pathways. Lines of researchĬhaix R., Fagny M., Cosin-Tomás M., Alvarez-López M., Lemee L., Regnault B., Davidson RJ., Lutz A., Kaliman P. She conducted her first postdoc in Dr Rozen’s lab at McGill University (Canada), where she studied the effects of high folic acid consumption during pregnancy on placenta and offspring neurodevelopment, with special attention to the associated epigenetic and transcriptional changes.Ĭurrently, she investigates the role of epigenetic mechanisms in the impact of environmental factors on offspring health, particularly on neurodevelopment during pregnancy and early childhood ( BiSC project, PACE consortium). She did her PhD at the University of Barcelona on the contribution of epigenetic mechanisms to ageing and Alzheimer’s disease (AD), and the effects of lifestyle interventions (physical exercise, dietary, stress reduction/meditation) on transcriptional and epigenetic modifications using animal models and human samples. Her background is in Biochemistry (BSc.) and Public Health (MSc.). Marta Cosin Tomas joined ISGlobal in 2020 as a postdoctoral researcher (Juan de la Cierva – formación fellowship).